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26 Home Depot Stores in South Carolina

StoreLocators
StoreLocators tracks real-time inventory and location data for Home Depot and 180+ other retailers. If you sell products at Home Depot or other retail stores, our Shopify app can display in-stock store locations directly on your product pages—no manual uploads required.
Download all 26 Home Depot store locations in South Carolina as a free CSV, including addresses, phone numbers, operating hours, and coordinates. This data is part of the largest free public directory of retail store locations, tracked in real-time by StoreLocators and updated daily.
Address City State Zip CountryPhoneHours
11785 Whiskey RdAikenSC29803🇺🇸(803) 648-6291
Sun8AM–8PM
Mon–Sat6AM–10PM
23427 Clemson BlvdAndersonSC29621🇺🇸(864) 964-0820
Sun8AM–8PM
Mon–Sat6AM–10PM
320 Gateway Village RoadBlufftonSC29910🇺🇸(843) 815-7000
Sun8AM–8PM
Mon–Sat6AM–10PM
47554 Northwood BlvdCharlestonSC29406🇺🇸(843) 569-3773
Sun8AM–8PM
Mon–Sat6AM–10PM
52008 Magwood DrCharlestonSC29414🇺🇸(843) 556-2447
Sun8AM–8PM
Mon–Sat6AM–10PM
65200 Fernandina RdColumbiaSC29212🇺🇸(803) 781-0877
Sun8AM–8PM
Mon–Sat6AM–10PM
7285 Forum DriveColumbiaSC29229🇺🇸(803) 419-9336
Sun8AM–8PM
Mon–Sat6AM–10PM
87701 Two Notch RdColumbiaSC29223🇺🇸(803) 736-1666
Sun8AM–8PM
Mon–Sat6AM–10PM
96607 Calhoun Memorial HwyEasleySC29640🇺🇸(864) 306-0137
Sun8AM–8PM
Mon–Sat6AM–10PM
103051 West Radio DriveFlorenceSC29501🇺🇸(843) 661-2597
Sun8AM–8PM
Mon–Sat6AM–10PM
1179 Woodruff Industrial LnGreenvilleSC29607🇺🇸(864) 284-0991
Sun8AM–8PM
Mon–Sat6AM–10PM
122490 N Pleasantburg DrGreenvilleSC29609🇺🇸(864) 232-0510
Sun8AM–8PM
Mon–Sat6AM–10PM
131339 S Pleasantburg DrGreenvilleSC29605🇺🇸(864) 236-0197
Sun8AM–8PM
Mon–Sat6AM–10PM
141385 W Wade Hampton BlvdGreerSC29650🇺🇸(864) 848-6083
Sun8AM–8PM
Mon–Sat6AM–10PM
151116 Highway 9 Byp WLancasterSC29720🇺🇸(803) 286-9700
Sun8AM–8PM
Mon–Sat6AM–10PM
165600 Sunset BlvdLexingtonSC29072🇺🇸(803) 359-1194
Sun8AM–8PM
Mon–Sat6AM–10PM
172213 North Highway 17Mount PleasantSC29466🇺🇸(843) 972-6800
Sun8AM–8PM
Mon–Sat6AM–9PM
1812262 Hwy 17 BypassMurrells InletSC29576🇺🇸(843) 357-3777
Sun8AM–8PM
Mon–Sat6AM–10PM
19951 Oak Forest LnMyrtle BeachSC29577🇺🇸(843) 916-2229
Sun8AM–8PM
Mon–Sat6AM–10PM
20620 Hwy 17 NNorth Myrtle BeachSC29582🇺🇸(843) 280-9908
Sun8AM–8PM
Mon–Sat6AM–10PM
212815 Home Depot BlvdRock HillSC29730🇺🇸(803) 909-2420
Sun8AM–8PM
Mon–Sat6AM–10PM
221614 Sandifer BlvdSenecaSC29678🇺🇸(864) 886-0633
Sun8AM–8PM
Mon–Sat6AM–10PM
23669 Fairview RoadSimpsonvilleSC29680🇺🇸(864) 963-7732
Sun8AM–8PM
Mon–Sat6AM–10PM
24121 Dorman Center DriveSpartanburgSC29301🇺🇸(864) 574-2922
Sun8AM–8PM
Mon–Sat6AM–10PM
252300 E Main StreetSpartanburgSC29307🇺🇸(864) 579-0382
Sun8AM–8PM
Mon–Sat6AM–10PM
26190 Marymeade DrSummervilleSC29483🇺🇸(843) 851-0468
Sun8AM–8PM
Mon–Sat6AM–10PM

Frequently Asked Questions

How many Home Depot stores are in South Carolina?
There are 26 Home Depot store locations in South Carolina, spread across 20 cities.
What cities in South Carolina have a Home Depot?
Home Depot has locations in 20 cities in South Carolina: Columbia, Greenville, Charleston, Spartanburg, Aiken, Anderson, Bluffton, Easley, Florence, Greer, and 10 more.
Where is the nearest Home Depot in South Carolina?
The city with the most Home Depot locations in South Carolina is Columbia with 3 stores. Other popular areas include Greenville and Charleston.
What are Home Depot store hours in South Carolina?
Most Home Depot stores in South Carolina are open 6AM to 10PM. However, hours may vary by location, so check individual store details for exact times.
Where else does Home Depot have stores?
Home Depot has store locations across 64 regions total. View all Home Depot locations to find a store near you.
Can I download a list of Home Depot stores in South Carolina?
Yes, you can download Home Depot store data as a free CSV including addresses, phone numbers, hours, and coordinates for South Carolina and all other locations. Data is updated daily. If you sell products at Home Depot or other retailers and run a Shopify or e-commerce store, StoreLocators can automatically track real-time in-stock inventory across 121,918+ retail locations and display it directly on your product pages—no manual uploads or developer help required.
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